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PH1 of a Kind is a video series for kids (and their caregivers, friends, and communities)
about living with primary hyperoxaluria type 1 (PH1).


PH1 of a Kind is a 4-part video series starring Isabelle, Luuk, Asha, and Will* — kids from around the world who have been diagnosed with PH1. Having this rare genetic disease means that some of their daily experiences are different from that of other kids, but PH1 doesn't define them — they’re special because of who they are.

New episodes will be published to this website over the next few months.

Not familiar with PH1? Click here to learn more.

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A lot of work goes into creating an animated series. These photos give you a look into the process and a sneak peek at what’s to come. Check back frequently for new photos.


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Primary hyperoxaluria type 1 (PH1) is a rare inherited disease of the liver in which overproduction of oxalate results in deposition of calcium oxalate crystals in the kidneys and urinary tract and can lead to the formation of recurrent kidney stones, progressive decline in kidney function, and multiorgan damage, when the disease advances.

Click here to learn more about PH1.

PH1 of a Kind is being developed by Alnylam Pharmaceuticals in partnership with the Oxalosis & Hyperoxaluria Foundation. To learn more about each organization and their work with PH1, click on the logos below.

*The characters featured in PH1 of a Kind are fictional. Any resemblance to actual people is purely coincidental.